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International Rabbit Day Reading Sept 24

Handing the surgeon’s scalpel to a robot

After decades of merely assisting doctors, are sophisticated machines ready to take charge?

Could a robot take over from a surgeon in the operating room? (knowablemagazine.org)

CRISPR infusion eliminates swelling in those with rare genetic disease

Company reports first benefits to patients from injecting the molecular gene-editing tool into the blood

CRISPR infusion eliminates swelling in those with rare genetic disease | Science | AAAS

Bluebird wins FDA approval of gene therapy for rare brain disorder

The therapy, cleared to treat cerebral adrenoleukodystrophy, is the product of more than a decade of work by Bluebird. It will cost $3 million.

Bluebird wins FDA approval of gene therapy for rare brain disorder | BioPharma Dive

Modeling embryonic circulation, researchers produce elusive precursor blood stem cells

Modeling embryonic circulation, team produces blood stem cells (fiercebiotech.com)

How the immune system shapes neurodegenerative diseases

How the immune system shapes neurodegenerative diseases: Trends in Neurosciences (cell.com)

Novo Nordisk Foundation issues $200M grant to apply quantum computing to life sciences, drug discovery

Novo Nordisk Foundation issues $200M grant to apply quantum computing to life sciences, drug discovery – Endpoints News (endpts.com)

China bets big on brain research with massive cash infusion and openness to monkey studies

Ambitious $746 million program aims to complement big neuroscience projects in Europe and the United States

China bets big on brain research with massive cash infusion and openness to monkey studies | Science | AAAS

The controversial embryo tests that promise a better baby

Some companies offer tests that rank embryos based on their risk of developing complex diseases such as schizophrenia or heart disease. Are they accurate — or ethical?

The controversial embryo tests that promise a better baby (nature.com)

Genetically modified purple tomatoes receive US approval

Genetically modified purple tomatoes receive US approval | News | Chemistry World

Four years in the making, AbbVie and Calibr provide first look into ‘switchable’ CAR-T program

Four years in the making, AbbVie and Calibr provide first look into ‘switchable’ CAR-T program – Endpoints News (endpts.com)

Can quantum computing really disrupt the pharma industry?

Will quantum computing be a massive breakthrough for the pharma industry? Or is it all just hype?

Can quantum computing really disrupt the pharma industry? | Sifted

Are $3M gene therapies the new normal? Experts say bluebird will be a test case for a market ready for prime time

Are $3M gene therapies the new normal? Experts say bluebird will be a test case for a market ready for prime time – Endpoints News (endpts.com)

Servier cuts ties with Allogene, ending complex CAR-T partnership

The French drugmaker terminated a nearly decade-old deal that helped Allogene emerge as the sector’s largest “off-the-shelf” cell therapy developer.

Servier cuts ties with Allogene, ending complex CAR-T partnership | BioPharma Dive

NIH launches the next stage of its ‘human genome project’ for the brain

NIH launches next stage of its ‘human genome project’ for the brain - STAT (statnews.com)

AlphaFold Developers Win $3-Million Breakthrough Prize in Life Sciences

DeepMind’s system for predicting the 3D structure of proteins is among five recipients of science’s most lucrative awards

AlphaFold Developers Win $3-Million Breakthrough Prize in Life Sciences - Scientific American

Multimodal biomedical AI

Multimodal biomedical AI | Nature Medicine

Transplantation of human neural progenitor cells secreting GDNF into the spinal cord of patients with ALS: a phase 1/2a trial

Transplantation of human neural progenitor cells secreting GDNF into the spinal cord of patients with ALS: a phase 1/2a trial | Nature Medicine

Post-infusion CAR TReg cells identify patients resistant to CD19-CAR therapy

Post-infusion CAR TReg cells identify patients resistant to CD19-CAR therapy | Nature Medicine

Variability of strain engraftment and predictability of microbiome composition after fecal microbiota transplantation across different diseases

Variability of strain engraftment and predictability of microbiome composition after fecal microbiota transplantation across different diseases | Nature Medicine

There’s New Proof Crispr Can Edit Genes Inside Human Bodies

The technique had largely been limited to editing patients’ cells in the lab. New research shows promise for treating diseases more directly.

There’s New Proof Crispr Can Edit Genes Inside Human Bodies | WIRED

FDA advisers back microbiota-based treatment for gut infection

FDA advisers back microbiota-based treatment for gut infection | BioPharma Dive