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National Happy Hour Day Reading Nov 12

New hope for sickle cell patients as UK trial of lab grown red blood cells begins

World first clinical test could be good news for people with rare blood groups and those who need frequent transfusions

New hope for sickle cell patients as UK trial of lab grown red blood cells begins | Medical research | The Guardian

Mapping brain genes in autism finds widespread changes, especially in visual regions

Mapping brain genes in autism finds widespread changes (fiercebiotech.com)

Adaptimmune to lay off up to 30% of staff as allogeneic ambitions stunted by cell line change

Adaptimmune to lay off up to 30% of staff amid pipeline shift (fiercebiotech.com)

Two former Stanford researchers nab a $41M launch round to learn the secrets of the ‘secretome’

Two former Stanford researchers nab a $41M launch round to learn the secrets of the ‘secretome’ – Endpoints News (endpts.com)

Mining from plants and fungi, CNS startup takes leap into psychoactive drugs — complete with $30M to kick things off

Mining from plants and fungi, CNS startup takes leap into psychoactive drugs — complete with $30M to kick things off – Endpoints News (endpts.com)

Brain implants that translate paralyzed patients’ thoughts into speech creep closer to reality

Brain implants that turn thoughts to speech closer to reality - STAT (statnews.com)

Unlocking the promise of mRNA therapeutics

Unlocking the promise of mRNA therapeutics | Nature Biotechnology

Psychedelics and Neural Plasticity: Therapeutic Implications

Psychedelics and Neural Plasticity: Therapeutic Implications | Journal of Neuroscience (jneurosci.org)

Electrical stimulation helps paralysed people walk again — and now we know why

Detailed gene-activity map could pave way for more precise treatments for many more people with spinal-cord injuries.

Electrical stimulation helps paralysed people walk again — and now we know why (nature.com)

Challenges in neoantigen-directed cancer therapeutics

Challenges in neoantigen-directed therapeutics: Cancer Cell

In a first, a fatal enzyme deficiency is treated in the womb

In a first, a fatal enzyme deficiency is treated in the womb - STAT (statnews.com)

Improving antitumor T cells

Disrupting cell cycle regulators can overcome anticancer T cell dysfunction

Improving antitumor T cells | Science

CRISPR cancer trial success paves the way for personalized treatments

‘Most complicated therapy ever’ tailors bespoke, genome-edited immune cells to attack tumours.

CRISPR cancer trial success paves the way for personalized treatments (nature.com)